Detalhe da pesquisa
1.
Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity.
Cell
; 164(3): 353-64, 2016 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26824653
2.
Publisher Correction: GDF15 mediates the effects of metformin on body weight and energy balance.
Nature
; 578(7796): E24, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-32051582
3.
GDF15 mediates the effects of metformin on body weight and energy balance.
Nature
; 578(7795): 444-448, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31875646
4.
Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15.
Proc Natl Acad Sci U S A
; 118(27)2021 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34187898
5.
Trappc9 deficiency causes parent-of-origin dependent microcephaly and obesity.
PLoS Genet
; 16(9): e1008916, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32877400
6.
Obesity-associated gene TMEM18 has a role in the central control of appetite and body weight regulation.
Proc Natl Acad Sci U S A
; 114(35): 9421-9426, 2017 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28811369
7.
Insulin-like peptide 5 is an orexigenic gastrointestinal hormone.
Proc Natl Acad Sci U S A
; 111(30): 11133-8, 2014 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-25028498
8.
Adult onset global loss of the fto gene alters body composition and metabolism in the mouse.
PLoS Genet
; 9(1): e1003166, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23300482
9.
Role for the obesity-related FTO gene in the cellular sensing of amino acids.
Proc Natl Acad Sci U S A
; 110(7): 2557-62, 2013 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23359686
10.
The gastrointestinal tract is a major source of the acute metformin-stimulated rise in GDF15.
Sci Rep
; 14(1): 1899, 2024 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38253650
11.
HypoMap-a unified single-cell gene expression atlas of the murine hypothalamus.
Nat Metab
; 4(10): 1402-1419, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36266547
12.
A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing.
Mol Metab
; 53: 101240, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33962048
13.
Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells.
Sci Rep
; 11(1): 2529, 2021 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33510216
14.
Murine neuronatin deficiency is associated with a hypervariable food intake and bimodal obesity.
Sci Rep
; 11(1): 17571, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34475432
15.
GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans.
Cell Metab
; 29(3): 707-718.e8, 2019 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30639358
16.
Contributions of Function-Altering Variants in Genes Implicated in Pubertal Timing and Body Mass for Self-Limited Delayed Puberty.
J Clin Endocrinol Metab
; 103(2): 649-659, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29161441
17.
Hypothalamic loss of Snord116 recapitulates the hyperphagia of Prader-Willi syndrome.
J Clin Invest
; 128(3): 960-969, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29376887
18.
Pro-opiomelanocortin modulates the thermogenic and physical activity responses to high-fat feeding and markedly influences dietary fat preference.
Endocrinology
; 148(11): 5331-8, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17717049
19.
Heterogeneity of hypothalamic pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing.
Mol Metab
; 6(5): 383-392, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28462073
20.
FTO is necessary for the induction of leptin resistance by high-fat feeding.
Mol Metab
; 4(4): 287-98, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25830092